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The Hyphen BioMed HIA (HIT) ELISA kits are standardized and optimized enzyme immuno-assay designed for measuring global heparin-dependent antibodies of the IgG or IgM, IgA isotype, or all three in human plasma or serum, or in any biological fluid where these antibodies must be measured.

The Enzyme Immuno Assays proposed are fully optimized, easy to perform, and provide reliable measurements with high reproducibility.

This optimized assay is designed with a protein-heparin complex, immobilized, stabilized and saturated, which allows total accessibility of heparin for the reaction. This reliable method then provides high reproducibility, high sensitivity and high specificity, by identifying all heparin-dependent antibodies, and by miming the binding mechanism of antibodies in vivo, on heparin present at the cell surface, especially on platelets or endothelial cells.

Controls are included in the kit.

Hyphen BioMed Product Catalog
Hyphen BioMed Product Catalog
 
   

 

 
Hyphen BioMed Price List

Hyphen BioMed Price List

   
 

HIT SALES SHEETS

 
See the Hit Assay Sales Sheet
 
Hit Assay Sales Sheet A New Test for the Diagnosis of Heparin Dependent Antibodies Associated with Type II Heparin Induced Thrombocytopenia
Hit Assay Sales Sheet A New Concept for Diagnosis of Heparin Induced Thromocytopenia
Hit Assay Sales Sheet Diagnosis of Heparin Induced Thromocytopenia
Hit Assay Sales Sheet Article - The Biomedical Scientist: Heparin-induced Thromocytopenia: a clinical paradox
   
HIT Slides-Chicago-05-2007
HIT Slides - Chicago - May 2007
  HIT ASSAYS Product Details          
Correlation with anti-HPF4 antibodies (anti-lgG)

The ZYMUTEST HIA, IgGAM ELISA kit, IgG Isotype, or IgG-IgM-IgA Isotype is a standardised and optimised enzyme immuno-assaydesigned for measuring global heparin-dependent antibodies of the IgG or IgM or IgA isotype, in human plasma or serum, or in any biological fluid where these antibodies must be measured. <more info>

Zymutest HIA IgGAM and Zymutest HIA IgG are now 510k cleared for in vitro medical diagnostic testing.

 
IgA Isotype
  Kit Product Details
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The ZYMUTEST HIA, IgA. Enzyme immuno-assay designed for measuring heparin-dependent antibodies of the IgA isotype, in human plasma or serum, or in any biological fluid where these antibodies must be measured <more info> <order now>
  Controls Product Details
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Artificial control using a “chimera antibody”, obtained by covalently coupling a rabbit anti-PF4 affinity purified antibody with human IgA. <more info> <order now>
 
Effects of platelet lysate addition
IgM Isotype
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The ZYMUTEST HIA, IgM. Enzyme immuno-assay designed for measuring heparin-dependent antibodies of the IgM isotype, in human plasma or serum, or in any biological fluid where these antibodies must be measured. <more info> <order now>

 

  Controls Product Details
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Artificial control using a “chimera antibody”, obtained by covalently coupling a rabbit anti-PF4 affinity purified antibody with human IgM. <more info> <order now>
                       
Incidence of the Various Heparin Dependent Antibody Isotypes
IgG Isotype
  Kit Product Details
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The ZYMUTEST HIA, IgG ELISA kit is a standardised and optimised enzyme immuno-assaydesigned for measuring the specific heparin-dependent antibodies of the IgG isotype, in human plasma or serum, or in any biological fluid where these antibodies must be measured <more info> <order now>
 
  Controls Product Details
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Artificial control using a “chimera antibody”, obtained by covalently coupling a rabbit anti-PF4 affinity purified antibody with human IgG. <more info> <order now>
Detection of heparin depandent antibodies
 
Whole Isotype (IgG/IgA/IgM)
  Kit Product Details
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The ZYMUTEST HIA, IgGAM ELISA kit, is a standardised and optimised enzyme immuno-assaydesigned for measuring global heparin-dependent antibodies of the IgG or IgM or IgA isotype, in human plasma or serum, or in any biological fluid where these antibodies must be measured. <more info> <order now>

  Controls
             
  HIT Controls for IgG Product Details
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Artificial control using a “chimera antibody”, obtained by covalently coupling a rabbit anti-PF4 affinity purified antibody with human IgG. <more info> <order now>

HIT Control for IgA Product Details
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Artificial control using a “chimera antibody”, obtained by covalently coupling a rabbit anti-PF4 affinity purified antibody with human IgA <more info> <order now>

HIT Control for IgM Product Details
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Artificial control using a “chimera antibody”, obtained by covalently coupling a rabbit anti-PF4 affinity purified antibody with human IgM.<more info> <order now>

 
 
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IgG/IgA/IgM (1/3 plate per isotype)
  Kit Product Details
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The ZYMUTEST HIA IgG/IgM/IgA ELISA kit, is a standardised and optimised enzyme immuno-assaydesigned for measuring global heparin-dependent antibodies of the IgG or IgM or IgA isotype, in human plasma or serum, or in any biological fluid where these antibodies must be measured.<more info> <order now>

 
  Controls
         
HIT Controls for IgG Product Details
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Artificial control using a “chimera antibody”, obtained by covalently coupling a rabbit anti-PF4 affinity purified antibody with human IgG. <more info> <order now>
HIT Control for IgA Product Details
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Artificial control using a “chimera antibody”, obtained by covalently coupling a rabbit anti-PF4 affinity purified antibody with human IgA <more info> <order now>
HIT Control for IgM Product details
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Artificial control using a “chimera antibody”, obtained by covalently coupling a rabbit anti-PF4 affinity purified antibody with human IgM.<more info> <order now>
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